Cytotoxic, acute toxicity and phytotoxic activity of Callicarpa macrophylla in various models
نویسندگان
چکیده
The present study describes the cytotoxic, acute toxicity and phytotoxic activities of Callicarpa macrophylla belonging to family Verbanaceae. Brine shrimps cytotoxic bioassay of crude extract of bark of C. macrophylla (CBE) showed 975.22 LD50 value and crude extract of leaves of C. macrophylla (CLE) showed no significant results. However, all the test animals were found absolutely safe in acute toxicity test. In phytotoxic assay against Lemna minor, CLE showed FI50 value of 464.55 and CBE showed no significant results. In conclusion, the CLE showed significant phytotoxic activity and therefore, could be a useful natural herbicidal.
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